DISEASES

Disease-gene associations mined from literature

Literature on SPAG9

SPAG9 [ENSP00000262013]

Mitogen-activated protein kinase 8-interacting protein 4; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction.

Synonyms:  SPAG9,  SPAG9p,  hSPAG9,  D6RHI8,  H0Y981 ...

Linkouts:  STRING  Pharos  UniProt  OMIM