DISEASES

Disease-gene associations mined from literature

Literature on C11orf73

C11orf73 [ENSP00000278483]

Chromosome 11 open reading frame 73; Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus; Belongs to the OPI10 family.

Synonyms:  C11orf73,  C11ORF73,  E9PJB2,  E9PPG8,  HIKESHI ...

Linkouts:  STRING  Pharos  UniProt