DISEASES

Disease-gene associations mined from literature

Literature on NME1-NME2

NME1-NME2 [ENSP00000376886]

C-myc purine-binding transcription factor PUF; Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Exhibits histidine protein kinase activity.

Synonyms:  NME1-NME2,  NME2,  NM23B,  NME2p,  hNME2 ...

Linkouts:  STRING  Pharos  OMIM