DISEASES

Disease-gene associations mined from literature

Literature on KIAA0101

KIAA0101 [ENSP00000300035]

Hepatitis C virus NS5A-transactivated protein 9; PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Synonyms:  KIAA0101,  G9G6C4,  G9G6D7,  H0YKX3,  H0YMA4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM