DISEASES

Disease-gene associations mined from literature

Literature on NCKIPSD

NCKIPSD [ENSP00000294129]

Wiskott-Aldrich syndrome protein-interacting protein; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

Synonyms:  NCKIPSD,  C9JC20,  C9JMQ4,  C9JSC3,  F8WCR8 ...

Linkouts:  STRING  Pharos