DISEASES

Disease-gene associations mined from literature

Literature on GGH

GGH [ENSP00000260118]

Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates; Belongs to the peptidase C26 family.

Synonyms:  GGH,  Q92820,  Q92820p,  hQ92820,  conjugase ...

Linkouts:  STRING  Pharos  UniProt  OMIM