DISEASES

Disease-gene associations mined from literature

Literature on ZNF746

ZNF746 [ENSP00000395007]

Parkin-interacting substrate; Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death; Zinc fingers C2H2-type

Synonyms:  ZNF746,  ZNF746p,  hZNF746,  C9JNZ9,  Q6NUN9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM