DISEASES

Disease-gene associations mined from literature

Literature on ARAP2

ARAP2 [ENSP00000302895]

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity); Ankyrin repeat domain containing

Synonyms:  ARAP2,  ARAP2p,  hARAP2,  ARAP2-001,  ARAP2-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM