DISEASES

Disease-gene associations mined from literature

Literature on ST13

ST13 [ENSP00000216218]

Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity); Belongs to the FAM10 family.

Synonyms:  ST13,  ST13p,  hST13,  B4E0U6,  B7ZA40 ...

Linkouts:  STRING  Pharos  UniProt  OMIM