DISEASES

Disease-gene associations mined from literature

Literature on SEPT7

SEPT7 [ENSP00000381992]

CDC10 protein homolog; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation; Septins

Synonyms:  SEPT7,  SEPT7p,  hSEPT7,  B4DNE4,  DKFZP586I031 ...

Linkouts:  STRING  Pharos  UniProt  OMIM