Disease-gene associations mined from literature

Literature on ICE1

ICE1 [ENSP00000296564]

Interactor of little elongator complex ELL subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies; Belongs to the ICE1 family.

Synonyms:  ICE1,  ICE1p,  hICE1,  KIAA0947,  Q9Y2F5 ...

Linkouts:  STRING  Pharos  UniProt