DISEASES

Disease-gene associations mined from literature

Literature on NR0B2

NR0B2 [ENSP00000254227]

Nuclear receptor subfamily 0, group B, member 2; Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box- containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1; Nuclear hormone receptors

Synonyms:  NR0B2,  NR0B2p,  hNR0B2,  Q15466,  Q15466p ...

Linkouts:  STRING  Pharos  UniProt  OMIM