DISEASES

Disease-gene associations mined from literature

Literature on DHX15

DHX15 [ENSP00000336741]

Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns; Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

Synonyms:  DHX15,  DHX15p,  hDHX15,  DHX15-001,  DHX15-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM