DISEASES

Disease-gene associations mined from literature

Literature on SCGB3A2

SCGB3A2 [ENSP00000296694]

Secretoglobin, family 3A, member 2; Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti- inflammatory effects in respiratory epithelium (By similarity). Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity); Secretoglobins

Synonyms:  SCGB3A2,  SCGB3A2p,  hSCGB3A2,  D6RBX5,  Q2L6B3 ...

Linkouts:  STRING  Pharos