DISEASES

Disease-gene associations mined from literature

Literature on LRR1

LRR1 [ENSP00000298288]

4-1BB-mediated-signaling molecule; May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Cyclophilin peptidylprolyl isomerases

Synonyms:  LRR1,  LRR1p,  hLRR1,  G3V5H2,  PPIL5 ...

Linkouts:  STRING  Pharos  UniProt