DISEASES

Disease-gene associations mined from literature

Literature on LIPI

LIPI [ENSP00000343331]

Membrane-associated phosphatidic acid-selective phospholipase A1-beta; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family.

Synonyms:  LIPI,  LOC375108,  Q5D1Q2,  Q6XZB0,  LPDL ...

Linkouts:  STRING  Pharos  UniProt  OMIM