DISEASES

Disease-gene associations mined from literature

Literature on PDCL3

PDCL3 [ENSP00000264254]

Viral IAP-associated factor 1; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination; Belongs to the phosducin family.

Synonyms:  PDCL3,  PDCL3p,  hPDCL3,  C9JST4,  Q9H2J4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM