DISEASES

Disease-gene associations mined from literature

Literature on HTR6

HTR6 [ENSP00000289753]

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling; 5-hydroxytryptamine receptors, G protein-coupled

Synonyms:  HTR6,  HTR6p,  hHTR6,  P50406,  P50406p ...

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