DISEASES

Disease-gene associations mined from literature

Literature on SH3BP5

SH3BP5 [ENSP00000373301]

SH3 domain-binding protein that preferentially associates with BTK; Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death; Belongs to the SH3BP5 family.

Synonyms:  SH3BP5,  SH3BP5p,  hSH3BP5,  A0A024R2G6,  A0A024R2J3 ...

Linkouts:  STRING  Pharos