DISEASES

Disease-gene associations mined from literature

Literature on LPHN3

LPHN3 [ENSP00000422533]

Calcium-independent alpha-latrotoxin receptor 3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Synonyms:  LPHN3,  LPHN3p,  hLPHN3,  ADGRL3,  B7Z2G2 ...

Linkouts:  STRING  Pharos