DISEASES

Disease-gene associations mined from literature

Literature on ECE2

ECE2 [ENSP00000384223]

Endothelin converting enzyme 2; Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit amyloid- beta peptide accumulation in brain. May also have methyltransferase activity.

Synonyms:  ECE2,  ECE2p,  hECE2,  EEF1AKMT4-ECE2,  F8WCL9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM