DISEASES

Disease-gene associations mined from literature

Literature on TAF2

TAF2 [ENSP00000367406]

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.

Synonyms:  TAF2,  TAF2p,  hTAF2,  A0A024R9E6,  E5RI28 ...

Linkouts:  STRING  Pharos  UniProt  OMIM