DISEASES

Disease-gene associations mined from literature

Literature on MXI1

MXI1 [ENSP00000331152]

Class C basic helix-loop-helix protein 11; Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX; Basic helix-loop-helix proteins

Synonyms:  MXI1,  MXI1p,  hMXI1,  B1ANN8,  F6U3F6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM