DISEASES

Disease-gene associations mined from literature

Literature on C9orf3

C9orf3 [ENSP00000364464]

Chromosome 9 open reading frame 3; Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart; M1 metallopeptidases

Synonyms:  C9orf3,  C9orf3p,  hC9orf3,  A0A024R9S7,  AOPEP ...

Linkouts:  STRING  Pharos  UniProt