DISEASES

Disease-gene associations mined from literature

Literature on KAT8

KAT8 [ENSP00000406037]

MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.

Synonyms:  KAT8,  KAT8p,  hKAT8,  KAT8-001,  KAT8-002 ...

Linkouts:  STRING  Pharos  UniProt