DISEASES

Disease-gene associations mined from literature

Literature on SHROOM3

SHROOM3 [ENSP00000296043]

Shroom family member 3; Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity); Belongs to the shroom family.

Synonyms:  SHROOM3,  SHROOM3p,  hSHROOM3,  Q8TF72,  KIAA1481 ...

Linkouts:  STRING  Pharos  UniProt  OMIM