DISEASES

Disease-gene associations mined from literature

Literature on NKX3-2

NKX3-2 [ENSP00000371875]

Bagpipe homeobox protein homolog 1; Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity); Belongs to the NK-3 homeobox family.

Synonyms:  NKX3-2,  NKX3-2-001,  P78367,  BAPX1,  NKX3B ...

Linkouts:  STRING  Pharos  UniProt