DISEASES

Disease-gene associations mined from literature

Literature on SGK2

SGK2 [ENSP00000340608]

Serum/glucocorticoid regulated kinase 2; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.

Synonyms:  SGK2,  SGK2p,  hSGK2,  F2Z3C8,  Q5H8Y5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM