DISEASES

Disease-gene associations mined from literature

Literature on CHD1L

CHD1L [ENSP00000358262]

Chromodomain helicase DNA binding protein 1-like; DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding; Belongs to the SNF2/RAD54 helicase family.

Synonyms:  CHD1L,  CHD1Lp,  hCHD1L,  Q86WJ1,  Q9H678 ...

Linkouts:  STRING  Pharos  UniProt  OMIM