DISEASES

Disease-gene associations mined from literature

Literature on RRAGD

RRAGD [ENSP00000358423]

Ras-related GTP-binding protein D; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.

Synonyms:  RRAGD,  Q9NQL2,  RRAGD-001,  RRAGD-002,  RRAGD-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM