DISEASES

Disease-gene associations mined from literature

Literature on SGPL1

SGPL1 [ENSP00000362298]

Sphingosine-1-phosphate aldolase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis; Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.

Synonyms:  SGPL1,  SGPL1p,  hSGPL1,  H7BXL7,  O95470 ...

Linkouts:  STRING  Pharos  UniProt  OMIM