DISEASES

Disease-gene associations mined from literature

Literature on MAP1LC3C

MAP1LC3C [ENSP00000349785]

Microtubule-associated protein 1 light chain 3 gamma; Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins.

Synonyms:  MAP1LC3C,  Q9BXW4,  Q9BXW4p,  hQ9BXW4,  2NCN ...

Linkouts:  STRING  Pharos  UniProt  OMIM