Disease-gene associations mined from literature

Literature on LYPD1

LYPD1 [ENSP00000380605]

Ly6/PLAUR domain-containing protein 1; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety; LY6/PLAUR domain containing

Synonyms:  LYPD1,  LYPD1p,  hLYPD1,  F8WD77,  MGC29643 ...

Linkouts:  STRING  Pharos  UniProt  OMIM