DISEASES

Disease-gene associations mined from literature

Literature on CCL25

CCL25 [ENSP00000375086]

Chemokine (C-C motif) ligand 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4; Belongs to the intercrine beta (chemokine CC) family.

Synonyms:  CCL25,  CCL25p,  hCCL25,  C9JDZ7,  O15444 ...

Linkouts:  STRING  Pharos  UniProt  OMIM