DISEASES

Disease-gene associations mined from literature

Literature on CDC14A

CDC14A [ENSP00000354916]

Dual specificity protein phosphatase CDC14A; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis; Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

Synonyms:  CDC14A,  CDC14Ap,  hCDC14A,  C9JSP6,  CDC14A-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM