DISEASES

Disease-gene associations mined from literature

Literature on AKIRIN2

AKIRIN2 [ENSP00000257787]

Akirin 2; Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity); Belongs to the akirin family.

Synonyms:  AKIRIN2,  AKIRIN2p,  hAKIRIN2,  Q53H80,  Q9NW35 ...

Linkouts:  STRING  Pharos  UniProt  OMIM