DISEASES

Disease-gene associations mined from literature

Literature on AES

AES [ENSP00000221561]

Amino-terminal enhancer of split; Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development; Belongs to the WD repeat Groucho/TLE family.

Synonyms:  AES,  AES-001,  AES-003,  AES-004,  AES-005 ...

Linkouts:  STRING  Pharos