DISEASES

Disease-gene associations mined from literature

Literature on GCC2

GCC2 [ENSP00000307939]

GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.

Synonyms:  GCC2,  GCC2p,  hGCC2,  B3KR21,  B8ZZA5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM