Literature associating U2AF35 and T-cell acute lymphoblastic leukemia
U2 small nuclear RNA auxiliary factor 1; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron; RNA binding motif containing
Synonyms: U2AF1, U2AF1p, hU2AF1, Q69YM7, U2AF1L5 ...