DISEASES

Disease-gene associations mined from literature

Literature associating SRCIN1 and superficial keratitis

SRCIN1 [ENSP00000484715]

SRC kinase signaling inhibitor 1; Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Synonyms:  SRCIN1,  LOC101929513,  SRCIN1p,  hSRCIN1,  J3KRM1 ...

Linkouts:  STRING  Pharos