DISEASES

Disease-gene associations mined from literature

Literature associating APELA and tetanus neonatorum

APELA [ENSP00000484618]

Apelin receptor early endogenous ligand; Hormone required for endoderm differentiation and heart morphogenesis during early development and for the adult cardiovascular system development by acting as a ligand for the apelin receptor (APLNR). Drives internalization of the apelin receptor. Acts as a motogen by promoting endoderm and mesendoderm cell migration during gastrulation by binding and activating the apelin receptor (By similarity); Belongs to the Elabela/Toddler family.

Synonyms:  ELABELA,  P0DMC3,  X5D2P3,  ELA,  P0DMC3p ...

Linkouts:  STRING  Pharos  UniProt