Literature associating APELA and cloacal exstrophy
Apelin receptor early endogenous ligand; Hormone required for endoderm differentiation and heart morphogenesis during early development and for the adult cardiovascular system development by acting as a ligand for the apelin receptor (APLNR). Drives internalization of the apelin receptor. Acts as a motogen by promoting endoderm and mesendoderm cell migration during gastrulation by binding and activating the apelin receptor (By similarity); Belongs to the Elabela/Toddler family.
Synonyms: ELABELA, P0DMC3, X5D2P3, ELA, P0DMC3p ...