DISEASES

Disease-gene associations mined from literature

Literature associating CD24 and extrahepatic bile duct carcinoma

CD24 [ENSP00000483985]

Small cell lung carcinoma cluster 4 antigen; May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity).

Synonyms:  CD24,  CD24p,  hCD24,  B6EC88,  B6EC88p ...

Linkouts:  STRING  Pharos