Disease-gene associations mined from literature

Literature associating WASF2 and substance dependence

WASF2 [ENSP00000483313]

Wiskott-Aldrich syndrome protein family member 2; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex; Wiskott-Aldrich Syndrome protein family

Synonyms:  WASF2,  WASF2p,  hWASF2,  B4E3J5,  Q8NBU0 ...

Linkouts:  STRING  Pharos  UniProt