DISEASES

Disease-gene associations mined from literature

Literature associating HNRNPDL and endometrial stromal sarcoma

HNRNPDL [ENSP00000483254]

Heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence; RNA binding motif containing

Synonyms:  HNRNPDL,  A0A024RDF6,  B4DGN3,  HNRPDL,  O14979 ...

Linkouts:  STRING  Pharos  UniProt