DISEASES

Disease-gene associations mined from literature

Literature associating PLCG2 and lymphoid leukemia

PLCG2 [ENSP00000482457]

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling; C2 domain containing phospholipases

Synonyms:  PLCG2,  PLCG2p,  hPLCG2,  H3BQV5,  P16885 ...

Linkouts:  STRING  Pharos  UniProt