DISEASES

Disease-gene associations mined from literature

Literature associating MED6 and nephronophthisis 4

MED6 [ENSP00000481920]

Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Synonyms:  MED6,  MED6p,  hMED6,  G3V4A5,  O75586 ...

Linkouts:  STRING  Pharos  UniProt