DISEASES

Disease-gene associations mined from literature

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Literature associating SPRY1 and CAKUT

SPRY1 [ENSP00000481675]

Sprouty homolog 1, antagonist of FGF signaling (Drosophila); May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

Synonyms:  SPRY1,  SPRY1p,  hSPRY1,  D6REX7,  D6RHD2 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.