Disease-gene associations mined from literature

Literature associating ADRA2B and familial adult myoclonic epilepsy 5

ADRA2B [ENSP00000480573]

Alpha-2 adrenergic receptor subtype C2; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.

Synonyms:  ADRA2B,  ADRA2Bp,  hADRA2B,  A2RUS0,  P18089 ...

Linkouts:  STRING  Pharos  UniProt