DISEASES

Disease-gene associations mined from literature

Literature associating ALOX5AP and myocardial infarction

ALOX5AP [ENSP00000479870]

Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes; Belongs to the MAPEG family.

Synonyms:  ALOX5AP,  ALOX5APp,  hALOX5AP,  P20292,  FLAP ...

Linkouts:  STRING  Pharos  UniProt